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Total Post-thyroidectomy Hypocalcemia After Preoperative Cholecalciferol Supplementation

RecruitingPhase 3Ages 18 Years - anyAllHôpital NOVO
NCT04775381 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective study evalue the inflence of pre operative vit D3 administration on post operative hypocalcemia in patients undergoing Total thyroidectomy

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patient ≥ 18 years old * Patient shall be operated on for a total thyroidectomy in one time for any indication * Written informed consent (IC) obtained * Patients with affiliation to the social security system Exclusion Criteria: • Medical history of : Thyroid or parathyroid surgery Hyperparathyroidism Granulomatosis flare-up * Hypocalcemia, hypercalcemia/ hypercalciuria, or symptom of Hypocalcemia, hypercalcemia/ hypercalciuria, not due to thyroid pathologies * Chronic kidney disease grade ≥4 * Severe liver failure * 25OHD supplementation within last 3 months before surgery * Malabsorption syndrome * Known hypersensitivity to vitamin D * Medical history of calcic lithiasis * Pregnant women * Vulnerable populations (guardianship or trusteeship) * Allergies to one of the components of the fruit juice
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What it tests

  • Vitamin D
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Where

6 sites
Department of General, Digestive and Endocrine Surgery
Auxerre, France
Department of ENT and maxillofacial surgery
Corbeil-Essonnes, France
Department of Head and Neck Surgery and ENT
La Roche-sur-Yon, France
Hospital Lariboisière, Paris X
Paris, France
Hospital Poissy/Saint-Germain
Poissy, France
Hospital René Dubos,
Pontoise, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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