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Surfactant for Neonatal Respiratory Distress Syndrome(NRDS) and Neonatal Acute Respiratory Distress Syndrome(NARDS)

Recruitingn/aAges 1 Minute - 24 HoursAllDaping Hospital and the Research Institute of Sur…
NCT04777760 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In preterm infants with neonatal respiratory distress syndrome (NRDS), exogenous pulmonary surfactant(PS) replacement therapy is one of the most important therapeutic breakthrough to reduce neonatal mortality. Nowadays, PS is commonly used in newborn infants with respiratory distress, but the incidences of bronchopulmonary dysplasia(BPD) and/or death are inconsistent. The result indicates that not all preterm infants with respiratory distress can be beneficial from PS. In 2017, the international neonatal ARDS (NARDS) collaborative group provides the first consensus definition for NARDS. And whether or not PS being beneficial for preterm infants with NARDS remains unknown.

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📋 Eligibility rules (as published)
Inclusion Criteria: Eligibility requirements for neonates were as follows: * The gestational age is less than 37 weeks and admitted to neonatal intensive care unit(NICU) in 24 h after birth * The neonates will be diagnosed with NRDS or NARDS * The neonates will be at least administrated one dose of surfactant Exclusion Criteria: one of the following criteria will be needed * major congenital anomalies * chromosomal abnormalities * upper respiratory tract abnormalities
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What it tests

  • one dose of surfactant replacement
  • two and more doses of surfactant replacement
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Where

1 site
Chen
Chongqing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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