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Adapted Physical Activity in Patients With Lower Limb Peripheral Arterial Disease

RecruitingNAAges 18 Years - anyAllCentre Hospitalier le Mans
NCT04800276 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The prevalence of peripheral arterial disease is 12.2% in France. Intermittent claudication is the most common symtom of this disease. During physical exercise, such as walking, blood oxygen (O2) requirements increase. The development of atherosclerosis in the lower limbs, causes narrowing of the arteries and limits the increase in blood flow required for muscular effort. Patients then experience muscle pain, the intensity of which gradually increases until it forces them to stop. After stopping, the pain subsides and disappears in less than 10 minutes. The location of the pain (calves and/or thighs and/or buttocks) is related to the location of the ischemia (distal in the calf, proximal in the thigh or buttock, or proximo-distal if several locations). This can have different consequences on the biomechanical parameters of walking and muscle activity. To date, the impact of this localiz

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patient with Lower Limb Peripheral Arterial Disease with IPSC \< 0.90, arterial stenosis in the lower limbs and intermittent claudication * No contraindication to physical activity * Socially insured patients over 18 ; * Patient who has signed the consent form. Exclusion Criteria: * Severe or unstable cardiopulmonary pathologies, contraindicating exercise training * Unstable angina or myocardial infarction \<3 months * Severe rheumatological pathology of the lower limbs * Amputee of a lower or upper limb fitted with a device * Extensive dermatosis of the lower limbs * Known NYHA grade III or IV heart failure * Known severe respiratory pathology * Parkinson's disease, hemiplegia or paraplegia * Adults subject to enhanced protection, deprived of their liberty by judicial or administrative decision * Persons unable to consent * Be in a period of exclusion from other interventional research. * Any event (injury, surgery, etc.) occurring during the protocol period that could have an impact on results.
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What it tests

  • muscle strengthening targeted on ischemic areas
  • global muscle strenghtening
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Where

1 site
Centre Hospitalier Du Mans
Le Mans, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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