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← Trials
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Exercise Effects on Adipose Tissue Structure and Function

RecruitingNAAges 18 Years - 40 YearsAllUniversity of Michigan
NCT04812314 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Participants will be randomized into one of two different experimental groups: 1) Exercise group and 2) No exercise (control group). Subject participation in the study will involve a series of metabolic tests before and after participants undergo a 10% weight loss program (with or without exercise training depending on group randomization). After completing this weight loss portion of the study, participants will then be required to adhere to a high calorie diet program to regain half of the weight the participant lost - followed by the same series of metabolic tests.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age: 18-40 * Body Mass Index: 27-45 kg/m2 * No regularly planned exercise/physical activity for at least 6 months * Women must have regularly occurring menses and must be premenopausal Exclusion Criteria: * Evidence/history of cardiovascular or metabolic disease * Medications known to affect lipid or glucose metabolism, or inflammation * Weight instability ≥ ± 6 pounds in the last 3 months * Tobacco or e-cigarette users * Women must not be pregnant or actively lactating
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What it tests

  • Exercise
  • No exercise
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Where

1 site
University of Michigan
Ann Arbor, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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