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Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis

Recruitingn/aAges any - 80 YearsAllTongji Hospital
NCT04847752 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a single-center prospective cohort study of predictive factors related to prognosis of ischemic stroke due to large-artery atherosclerosis. From March 1, 2021 to December 31, 2026, 1000 patients with ischemic stroke due to large-artery atherosclerosis who are admitted to the Department of Neurology or Neurosurgery, Tongji Hospital are going to be recruited. Detailed clinical data in emergency room and in-hospital will be obtained from the medical record reviews, and the National Institutes of Health Stroke Scale (NIHSS) and Modified Rankin Scale (mRS) score will be done by certified neurologists to assess the severity of the disease in acute stage and treatment outcome during the follow-up. All cases will undergo routine blood tests, brain magnetic resonance imaging (MRI) and cerebral vascular examination, such as TCD, CTA, HRMR or DSA. The investigators will analyze the in-hosp

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📋 Eligibility rules (as published)
Inclusion Criteria: * Ischemic stroke due to large-artery atherosclerosis has been proved by clinical symptoms and imaging examinations. * Symptomatic superior arch stenosis \>50% * Asymptomatic superior arch stenosis was \>70% * written informed consent was obtained from patients or their surrogates before enrollment. Exclusion Criteria: * Brain CT or MRI showing cerebral hemorrhage (excluded ischemic stroke with hemorrhage transformation) * With severe systemic disease, are expected to survive \< 3 months * Patients will not able to provide continuous follow-up information
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What it tests

  • carotid artery stenting
  • carotid endarterectomy
  • Aspirin
  • Clopidogrel
  • Anticoagulant
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Where

1 site
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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