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Periodontal Assessment of a Bariatric Care Population

Recruitingn/aAges 18 Years - anyAllQueen Mary University of London
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In plain words

What the trial is, and whether it could suit you

Our primary aim is to investigate the prevalence and severity of Periodonotal Disease (PD) in a population of obese patients. Our secondary objectives are to: Investigate inflammatory biomarkers that have been associated with PD in the saliva of obese patients. Investigate the association of FTO gene (Obesity) polymorphisms with the prevalence of PD in this population. Investigate and describe the subgingival microbial flora in obese patients with PD from subgingival dental plaque samples as well as the salivary samples.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: Each subject must meet all of the following inclusion criteria to be enrolled in the study: 1. Subject must be over 18 years of age. 2. Subject must have a BMI of higher or equal to 30 kg/ m2 3. Subject must have voluntarily given written informed consent. Exclusion Criteria: Subjects meeting any of the following exclusion criteria are not to be enrolled in the study: 1. Subject is currently involved in other research involving the use of antibiotics or novel or unknown medications. 2. Self-reported pregnancy. 3. Subject is on chronic treatment (i.e., two weeks or more) with specific medications known to affect periodontal status (phenytoin or cyclosporine) within one month of baseline visit. 4. Subject knowingly has HIV or Viral Hepatitis. 5. Patients are completely edentulous. 6. Subject with uncontrolled systemic illnesses. 7. Subject is not capable to give informed consent. 8. Subjects on chronic antibiotic therapy (ie two weeks or more in the previous month).
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What it tests

  • Not listed
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Where

4 sites
Barts Health NHS Trust Dental Hospital
London, United Kingdom
Centre for Oral Clinical Research (COCR)
London, United Kingdom
St Bartholomew's Hospital, Barts Health NHS Trust
London, United Kingdom
Luton and Dunstable University Hospital
Luton, United Kingdom
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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