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โ† Trials
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Female Fertility, Environmental Agents and Stress Oxidant

Recruitingn/aAges 18 Years - 43 YearsFemaleUniversity Hospital, Tours
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In plain words

What the trial is, and whether it could suit you

Synthetic products used in industrial, pharmaceutical, agro-alimentary or agricultural fields are found in our environment. Thus, humans could be simultaneously exposed to several of these pollutants. Furthermore, these environmental agents exert or could exert adverse actions on fertility, by altering gamete and embryo quality through endocrine disruptor effects or through increase in oxidative stress in gonads (cellular pathway known to be involved in several human reproductive pathologies). In this context, the objectives of the present project are to obtain descriptive and analytical data on woman and oocyte exposure to several environmental agents (bisphenols, ethynylestradiol and glyphosate). The relation between these pollutant measures in follicular fluid and urine (from women receiving follow-up of in vitro fertilization (IVF) protocol in the University hospital of Tours, Franc

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Woman aged 18 to 43 years old * First oocyte puncture (IVF rank = 1) Exclusion Criteria: * Opposition to data processing * IVF rank equal or greater than 2 * Egg donation * Intracytoplasmic Sperm Injection with testicular biopsy * Intracytoplasmic Sperm Injection with self-preservation straw * Sperm donation
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What it tests

  • Blood sample
  • Urine sample
  • Follicular fluid and granulosa cells sample
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Where

1 site
Department of Reproductive Medicine and Biology, Univesity Hospital, Tours
Tours, France
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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