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Complete Mesocolic Excision in Comparison With Conventional Surgery for the Right Colon Cancer

RecruitingNAAges 18 Years - 85 YearsAllUniversity of Turin, Italy
NCT04871399 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

An Italian randomized controlled trial parallel-group in patients with a malignant tumor of the right or proximal transverse colon requiring right hemicolectomy.

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📋 Eligibility rules (as published)
Inclusion Criteria: * American Society of Anesthesiologists(ASA) grade I-III. * Right colon cancer (\*The right-sided location of the cancer is defined as the location from the caecum up to the proximal third of the transverse colon), preoperative assessment of tumor stage T2-T4a, any N or T any N+ according to the National Comprehensive Cancer Network(NCCN) clinical practice guidelines in oncology: colon cancer version 2.2015); no distant metastasis. * Informed consent Exclusion Criteria: * Age \> 85 years old. * T1, N0 * T4b, any N * BMI \> 30. * Metastatic disease (Abdominal and chest CT scan will be mandatory to exclude distant metastasis.) * American Society of Anesthesiologists(ASA) grade IV. * History of cancer in recent 5 years. * Need for Emergency surgery. * Infectious disease requiring treatment. * Pregnancy. * Use of systemic steroids. * No history of familial adenomatous polyposis, ulcerative colitis or Crohn's disease.
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What it tests

  • Conventional Right hemicolectomy (Non-CME)
  • Right hemicolectomy with CME+CVL
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Where

14 sites
Ospedale della Misericordia
Grosseto, Italy
Ospedale Città di Sesto San Giovanni
Sesto San Giovanni, Italy
S. Andrea Hospital
La Spezia, Italy
Candiolo Cancer Institute - IRCCS
Candiolo, Italy
Ospedale E. Agnelli Pinerolo
Pinerolo, Italy
Maggiore Bellaria Hospital, Bologna
Bologna, Italy
Università degli Studi di Ferrara
Ferrara, Italy
Ospedale Policlinico San Martino
Genova, Italy

…and 6 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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