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Central Vein Stenosis Due to Dialysis Catheter Insertion in Subclavian Compared to Jugular Vein

RecruitingNAAges 18 Years - anyAllSkane University Hospital
NCT04871568 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Central vein stenosis (CVS) is a well-known complication of central venous catheterization, especially after insertion of temporary hemodialysis catheters (tHDC). Incidence and prevalence differ between studies, and exact figures are hard to tell since proper venographies seldom are performed unless the patient is symptomatic. Most tHDC are placed in the jugular or femoral veins as catheters in the subclavian veins have been shown to result in CVS to a greater degree. However, some studies are equivocal and there are several advantages with the subclavian vein such as a lower risk for infectious and thrombotic complications, longer durability (thereby avoiding placement of a new catheter with repeated tissue trauma), increased comfort during insertion and use, less effect on blood flow if the patient moves the head, easier to mobilize. The studies on CVS incidence originate from the 19

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults (18 years of age or older). * In need of a tCDC with an expected treatment time of at least 7 days. * Informed consent. Exclusion Criteria: * Intravenous pacemaker or a PICC-line via right-sided central veins in situ. * Known right-sided CVS. * AV fistula on the right upper extremity. * History of central venous vascular interventions including stents, dilatations and more (but not previous central venous catheterization). * Central venous catheter in the right internal jugular vein or in the right subclavian vein in situ. * Either the right jugular vein or the right subclavian vein unavailable for catheterization due to, e.g., local skin infection, thrombosis or inability to visualize the vein with ultrasound. * Known allergy to iodinated contrast agents. * BMI \>35 kg/m2. * No study physician available for the catheterization.
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What it tests

  • Temporary central dialysis catheterization
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Where

1 site
Skånes universitetssjukhus
Lund, Sweden
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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