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Circadian Rhythms in Postmenopausal Women

RecruitingNAAges 45 Years - 65 YearsFemaleJulie Pendergast
NCT04893226 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a randomized, parallel two-arm clinical trial design to study the efficacy of time-restricted feeding on metabolic risk in postmenopausal women, who may be particularly vulnerable to disruption of circadian eating rhythms and the associated metabolic dysfunction. It is hypothesized that time-restricted feeding will improve insulin sensitivity, glucose tolerance, body weight, and other metabolic parameters in metabolically-unhealthy postmenopausal women.

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📋 Eligibility rules (as published)
Inclusion Criteria: * postmenopausal women * age 45-65 years * prediabetic or have at least 2 features of metabolic syndrome Exclusion Criteria: * on hormone therapy * diabetes * heart disease * alcohol consumption of \>2 drinks per day * significant circadian disruption * having care-taking responsibilities that significantly affect sleep * shift work or irregular lifestyle * uncontrolled sleep apnea or other uncontrolled sleep disorder * extreme early or late chronotypes * significant psychiatric disorders * taking ADHD medications * diagnosed dysregulated eating behaviors * smoking \>5 cigarettes/day or 30 pack-year history * participating in formal weight loss program * not weight stable
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What it tests

  • Time-Restricted Feeding (TRF)
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Where

1 site
University of Kentucky
Lexington, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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