🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Patient Reported Outcomes Following Cancer of the Rectum

Recruitingn/aAges 18 Years - 100 YearsAllUniversity Hospital Gregorio Marañón
NCT04936581 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The surgical management of rectal cancer includes a Total Mesorectal Excison (TME); depending on the height of the tumor, the problem of preservation of the anal sphincter arises, being able to perform a low anterior resection, an ultra-low anterior resection (RAUB) or an intersphincteric dissection. In some cases invading the sphincters or the puborectalis muscle, an abdominoperineal resection needs to be performed, being the gold standard in this particular situation so far. TME can be performed by open, laparoscopic, robotic or transanal approaches, as long as the oncological principles for the resection are achieved. Unfortunately, up to 90% of these patients will present a change in bowel habit, ranging from an increased frequency of bowel movements to the degree of fecal incontinence or evacuation dysfunction. Of these patients, 25-50% will have a severe alteration in the quality

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Patients over 18 years old * Informed consent * Diagnosed with rectal cancer located below the peritoneal reflection, defined by preoperative MRI * Open, laparoscopic, robotic or Transanal Total Mesorectal Excision (taTME) approaches * Patients with/without derivative stoma * Patients with/without neoadjuvant treatment Exclusion Criteria: * Upper rectal cancer, located above the peritoneal reflection * Previous radical prostatectomy * Previous pelvic radiotherapy * Rectal resection without primary anastomosis * Intraoperative findings of peritoneal carcinomatosis * Stage IV disease * Multivisceral or en-bloc resection, which includes uterus, prostate, vagina or bladder * Rectal resection due to a benign condition * Rectal resection due to a recurrence of rectal cancer (previous anterior resection or another primary neoplasm) * Rectal resection following a 'watch \& wait' program * Emergency surgery * Previous derivative colostomy * Inflammatory bowel disease
💊

What it tests

  • Open Total Mesorectal Excision
  • Laparoscopic Total Mesorectal Excision
  • Robotic Total Mesorectal Excision
  • Transanal Total Mesorectal Excision
📍

Where

2 sites
University Clinic of Navarre
Madrid, Spain
University Hospital Gregorio Marañón
Madrid, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy