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Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children

Recruitingn/aAges 5 Years - 13 YearsAllUniversity of Colorado, Denver
NCT04993859 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The over-arching aim of this study is to evaluate the effects of two specific anti-cancer chemotherapies, vincristine and doxorubicin, on bladder function and urine composition.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Children aged 5-13 years old * A history of cancer * Treatment with a chemotherapy regimen including VCR and/or DOX * Completion of chemotherapy at least one year prior to study enrollment and survey completion. Exclusion Criteria: * Patients with a: * Primary pelvic tumor * Pelvic irradiation * Pre-existing bladder/bowel dysfunction * Spinal defects * Neurologic disorder * Neuro-oncologic tumor or brain metastasis * Cyclophosphamide or ifosfamide therapy
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What it tests

  • Non-invasive Urodynamic Test (niUDS)
  • Urinary proteomic screen
  • Dysfunctional Voiding Symptom Score Survey (DVSS)
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Where

1 site
Children's Hospital Colorado
Aurora, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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