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Regenerative Peripheral Nerve Interfaces to Treat Painful Digit and Hand Neuromas After Amputation

Recruitingn/aAges 18 Years - anyAllMedstar Health Research Institute
NCT05008185 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study is being done to demonstrate the effectiveness of Regenerative Peripheral Nerve Interfaces (RPNI) surgery in treating symptomatic neuromas of the hand and digits following amputation compared to standard of care using a Prospective, Observational Trial

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📋 Eligibility rules (as published)
Inclusion Criteria: * 18 years or older * History of unilateral digit, multiple digit, or partial hand amputation * Discrete neuroma pain on clinical exam * Following standard of care (SOC), confirmation through a local block and/or ultrasound imaging will be performed if indicated * Must be seen by a hand therapist for at least 6-week trial of desensitization therapy Exclusion Criteria: * Patients with previous surgical treatment for symptomatic neuromas of the digits or hand * Patients with other major injuries more proximal in the ipsilateral extremity that cause chronic pain or functional loss * women pregnant at time of enrollment * prisoners * adults who are unable to consent
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What it tests

  • Regenerative Peripheral Nerve Interface (RPNI) surgery
  • Traction Neurectomy
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Where

2 sites
The Curtis National Hand Center at Medstar Union Memorial Hospital
Baltimore, United States
University of Michigan Plastic Surgery
Ann Arbor, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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