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Baby Brain Recovery Study

Recruitingn/aAges 0 Years - 24 MonthsAllUniversity of Wisconsin, Madison
NCT05013736 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study will be a longitudinal multiple-visit observational study, done to identify possible bioindicators of recovery and repair of motor corticospinal pathways which may be targeted by future interventions in infants with perinatal stroke. 65 participants will be recruited and complete 1 visit at time point 1 (0-2 months), and 2 visits at each timepoints 2-5 with windows of +- 4 weeks (3-6 months, 12 months, 18 months and 24 months). Visits will consist of Magnetic Resonance Imaging (MRI) assessment during the child's natural sleep, Transcranial Magnetic Stimulation (TMS), and Motor Behavioral Assessments.

Sign in to get the eligibility rules as simple questions to take to your doctor.

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📋 Eligibility rules (as published)
Main Inclusion Criteria: * Infants with corrected gestational age between term age and 24 months of age at study enrollment * Radiologically-confirmed acute unilateral or bilateral brain lesions, including perinatal stroke, neonatal hemorrhagic or thrombotic stroke, involving the motor cortex and/or subcortical structures, and intracranial hemorrhage, involving the motor cortex and/or subcortical white matter, periventricular leukomalacia, and hypoxic-ischemic encephalopathy (HIE) * English-speaking parent/legal guardian (able to provide consent) Main Exclusion Criteria: * Other neurologic disorders unrelated to perinatal stroke/brain bleed/HIE * Metabolic disorders * Disorders of Cellular Migration and Proliferation * Acquired Traumatic Brain Injury
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What it tests

  • Magnetic Resonance Imaging
  • Behavioral Assessments
  • Non invasive Transcranial Magnetic Stimulation
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Where

1 site
University of Wisconsin School of Medicine and Public Health
Madison, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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