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Economic Incentives and vDOT for Latent Tuberculosis Infection

RecruitingNAAges 18 Years - anyAllJohns Hopkins University
NCT05022862 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to evaluate a novel and scalable intervention that combines Video Directly Observed Therapy (vDOT) and financial incentives to promote completion of treatment for latent tuberculosis. Adult participants who are initiating treatment for latent tuberculosis will be recruited from the Baltimore City Health Department. The primary hypothesis is that the incentive intervention will increase the percentage of participants that complete the treatment for latent tuberculosis above the completion rates of participants receiving usual care.

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📋 Eligibility rules (as published)
Inclusion Criteria: * 18 years old or older, * diagnosed with latent TB and determined to be appropriate for latent TB treatment by participants clinicians * reside in Baltimore metro area * speaks English or Spanish, or a language for which there is a short form available via the Johns Hopkins Medicine Institutional Review Board * prescribed 3 months Isoniazid/Rifapentine, prescribed 3 months Isoniazid/Rifampin, or 4 months Rifampin Exclusion Criteria: * younger than 18 years old * diagnosed with active TB * prescribed an alternative treatment regimen for latent TB * pregnant women (as determined by non-study directed clinical evaluation; BCHD performs urine pregnancy testing on women of child bearing age when indicated) * participant's spoken language does not have a translated long or short consent form
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What it tests

  • Usual Care
  • Video Directly Observed Therapy alone
  • Video Directly Observed Therapy plus Financial Incentives
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Where

1 site
Baltimore City Health Department, and Baltimore metropolitan area clinics and health departments
Baltimore, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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