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Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise

Recruitingn/aAges 8 Years - 25 YearsAllMasonic Cancer Center, University of Minnesota
NCT05025774 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to more accurately assess cardiac function, ventilation and exercise capacity in a non-invasive fashion, and to better characterize exercise intolerance in the setting of three populations of individuals with chronic diseases of childhood (acute lymphoblastic leukemia (ALL), chronic lung disease (CLD) of prematurity, and post-heart transplant (HT))

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📋 Eligibility rules (as published)
Inclusion Criteria: * Cases: * Acute lymphoblastic leukemia survivor, OR living with chronic lung disease of prematurity, OR living with heart transplant * 8-25 years old * Height: ≥ 48 inches * Ambulatory without assistance * English speaking * Normotensive (\<95th percentile for age; okay if managed with antihypertensive medication) * SpO2 \>92% * Not pregnant * ALL survivor specific: must have completed therapy ≥ 3 months prior to study entry * Controls * 8-25 years old * Height: ≥ 48 inches * Ambulatory without assistance * English speaking * No history of arrhythmia or known cardiac dysfunction at baseline * Normotensive (\<95th percentile for age; okay if managed with antihypertensive medication) * SpO2 \>95% * Not pregnant Exclusion Criteria: * Cases: * ALL specific: received cranial radiation, bone marrow transplant recipients * Investigator or patient's primary physician deems the patient unsuitable for the study * Controls: * History of malignancy, CLD or HT or any other diagnosis which may reduce cardiorespiratory function * Investigator deems the patient unsuitable for the study
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What it tests

  • Physical activity
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Where

1 site
Masonic Cancer Center
Minneapolis, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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