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The Association Between Radiation Dermatitis and Skin Microbiome in Breast Cancer Patients

Recruitingn/aAges 18 Years - 70 YearsFemaleFudan University
NCT05032768 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The breast cancer patients who received radiotherapy after mastectomy and breast reconstruction will be enrolled. The skin microbiome before radiotherapy and its changes after radiotherapy will be analyzed systematically to find out whether the skin microbiome is associated with the severity of radiation dermatitis.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Female patients 2. Invasive breast cancer confirmed by pathology 3. Underwent mastectomy and breast reconstruction 4. Radiotherapy after breast reconstruction 5. ECOG score 0-1 6. Signed informed consent Exclusion Criteria: 1. Previous breast or chest radiotherapy 2. Other serious skin diseases (systemic lupus erythematosus, skin sclerosis, et al) and cannot receive radiotherapy 3. Pregnant women 4. Patients who are unwilling or unable to receive regular follow-up.
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What it tests

  • post-operative radiotherapy
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Where

1 site
Fudan University Shanghai Cancer Center
Shanghai, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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