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Clinical Features Associated With Restless Legs Syndrome.

Recruitingn/aAges 18 Years - anyAllUniversity Hospital, Montpellier
NCT05044520 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Restless legs syndrome (RLS) is a chronic neurological disorder characterized by an urge to move the legs at night when at rest. RLS can lead to a sleep deprivation, increased falling risk, daytime sleepiness, depression and decreased quality of life. Dopamine agonists, alpha-2-delta ligands and opiates are key medications for RLS. The natural course of RLS is very heterogeneous with a risk of increasing the severity of symptoms over the years despite the use of drugs and recommended dosages. Many comorbidities can make RLS worse. Augmentation syndrome is the main complication of dopamine agonists. However, only a few studies have addressed the clinical, biological and pharmacological factors associated with the evolution of the severity of RLS. The objective of this study is to assess the evolution of RLS symptoms severity as function of RLS phenotype, comorbidities and RLS medication,

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📋 Eligibility rules (as published)
Inclusion criteria: * Adults subjects * Restless legs syndrome diagnosis * Member of the restless legs syndrome association * French speaking * Able to understand the study * Signed written informed consent * Affiliated to social security Exclusion criteria: \- Vulnerable subject : subject deprived of liberty or protected by law (trusteeship, legal guardianship)
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What it tests

  • Not listed
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Where

1 site
Uhmontpellier
Montpellier, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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