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โ† Trials
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Effect of Early Administration of TXA in Adult Hip Fractures

RecruitingPhase 2, Phase 3Ages 18 Years - anyAllAscension Health
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In plain words

What the trial is, and whether it could suit you

This is a prospective clinical study designed to assess blood loss in intracapsular and extracapsular hip fractures undergoing operative fixation at a Level II trauma center. It is well established in the orthopedic literature that tranexamic acid (TXA) decreases blood loss and need for postoperative blood transfusion in hip fracture patients as well as total joint arthroplasty patients. A typical dosing pattern, and the dosing pattern employed at our institution, is 1 gram IV infused prior to incision followed by 1 gram IV infused at the time of wound closure.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * 1\. All adult (18 years old or older) hip fracture patients presenting with an acute hip fracture and undergoing operative fixation Exclusion Criteria: 1. Polytrauma patients 2. Previous operation on the ipsilateral hip 3. Patients with coagulopathies (Factor V Leiden, Sickle Cell Anemia, Etc.) 4. Patients with \< 6-month history of thromboembolic event (DVT/PE), Stroke, Cardiac Stents, or Myocardial Infarction (MI) 5. History of seizure disorder 6. Patients on birth control 7. Pregnant Women 8. Prisoners 9. Active thromboembolic disease (DVT/PE, MI, Stroke)
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What it tests

  • Tranexamic acid
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Where

1 site
Ascension Genesys Hospital
Grand Blanc, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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