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Assessment in Patients With Essential Trigeminal Neuralgia of Nerve Involvement by MRI in DTI and Functional Connectivity in "Resting State"

RecruitingNAAges 18 Years - anyAllFondation Ophtalmologique Adolphe de Rothschild
NCT05051072 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Essential trigeminal neuralgia is the most common facial pain. In forms resistant to drug and disabling treatments, surgical treatment may be offered to the patient. The type of intervention will be conditioned by the presence or absence of a vasculo-nervous conflict objectified by MRI(Magnetic resonance imaging) Morphological MRI with contrast injection does not always allow an accurate assessment of trigeminal nerve damage in patients with essential facial neuralgia. Despite advances in the anatomical definition of high-resolution MRI, the correlation between a vascular conflict visible on MRI and present during surgery and prolonged postoperative clinical improvement remains insufficient These data raise the question of additional imaging sequences to assess the distressing characteristics of NT in addition to the usual anatomical criteria for compression By performing during morpholo

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult patients (18 years and over); * Supported in the neurosurgery department or at the assessment and treatment center for pain for unilateral essential trigeminal neuralgia with search for vasculo-nervous conflict; Exclusion Criteria: * Patient with neurodegenerative or inflammatory neurological pathology; * Patient who has already been operated on for a DMV; * Absolute contraindication to MRI * Patient benefiting from a legal protection measure; with impaired judgment skills or unable to receive information; * Pregnant or breastfeeding women
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What it tests

  • Assessment of the trigeminal nerve by diffusion tensor MRI and in "resting state" in the context of essential neuralgia
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Where

1 site
Fondation Ophtalmologique de Rothschild
Paris, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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