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Renal Cancer Detection With Liquid Biopsy

Recruitingn/aAges 18 Years - anyAllZealand University Hospital
NCT05060783 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Glycosaminoglycans (GAGs) were significantly altered in localized as well advanced RCC compared to healthy samples. In addition, GAG scores correlated with progression-free survival and overall survival (OS) in a prospective cohort of patients with metastatic ccRCC and localized RCC. However, it is still unknown whether alterations in plasma and urine GAGs are exquisitely specific to RCC or are shared by other benign lesions in the kidney, such as angiomyolipomas, oncocytomas, or PEComa.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Patients who underwent CT-scan with suspicion of renal tumor and the scans show no sign of renal cancer. 2. For patient with ccRCC or oncocytoma, they should have a histological verified tumor (Biopsy or surgical specimen) 3. Sign up information consent 4. Can perform protocol procedure Exclusion Criteria: 1. Non-clear cell Renal cell carcinoma 2. RCC with pure sarcomatoid differentiation, also called sarcoma of the kidney 3. Use of heparin for concurrent disease in need of blood dilution (e.g. ongoing deep vein thrombosis or lung emboli). Note: use of of heparin for thrombus prophylaxis in conjunction with primary surgery or postoperatively ≤4 weeks will be allowed.
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What it tests

  • GaGnostic
  • GaGnostic
  • GaGnostic
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Where

1 site
Zealand University Hospital
Roskilde, Denmark
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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