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Re-assessment of Appendicitis Evaluation During Laparoscopic Appendectomy, Peritoneal Irrigation During Laparoscopic Appendectomy Does the Grade of Contamination Matter?

Recruitingn/aAges 18 Years - 69 YearsAllNiguarda Hospital
NCT05075252 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Type: prospective observational multicenter trial. Population of interest: adult patients undergoing laparoscopic appendectomy for acute appendicitis. Hypothesis : laparoscopic lavage during laparoscopic appendectomy is a practice that should be used in selected patients according to the intraperitoneal grade of contamination and grade of appendicitis. Nonregulated use of laparoscopic lavage cannot be considered superior to suction only considering recent evidence. Few RCT available addressing this issue are available, but any with a high methodological quality. Aim: The aim of this study is to investigate the impact of laparoscopic lavage during laparoscopic appendectomy on the postoperative incidence of intrabdominal abscesses, stratifying patients in different clusters according to a defined classification considering the intraperitoneal contamination and grade of appendicitis.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients between 18 and 69 years old * Surgical laparoscopic approach for AA * Intra-operative and histological diagnosis of AA Exclusion Criteria: * Patients \< 18 years old or \> 69 years old * Previous appendectomy * Previous appendicitis treated conservatively * Open approach for surgery or intra-operative conversion * Co-existence of other intra-abdominal infections (IAI) * Patients with immunodeficiency * Patients treated with steroid, immunosuppressant, or CHT within previous 6 months
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What it tests

  • laparoscopic lavage
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Where

1 site
ASST GOM Niguarda
Milan, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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