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Influence of Presurgical Orthodontic Molding on the Growth of Newborns With Unilateral Cleft Lip Palate

RecruitingNAAges 1 Day - 2 YearsAllUniversity of Erlangen-Nürnberg
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In plain words

What the trial is, and whether it could suit you

Orofacial clefts are the second most common birth deformity and vary in etiology and phenotype, e.g. isolated cleft palate, cleft lip or cleft lip palate. Especially newborns with unilateral complete cleft lip and palate (UCLP) present severe facial asymmetries auch as a broad and flat ala of the nose, a deviation of the columella and the philtrum to the non cleft side. Since postnatal asymmetries can even remain after surgical lip closure in a alleviated shape, therapeutic presurgical orthodontic approaches to improve symmetrie of the nose and to achieve ideal conditions for lip surgery are essential. Presurgical orthodontic treatment for newborns with UCLP start within the first days after birth to separate oral and nasal cavitiy, to improve breathing and feeding and to regulate growth of the maxillary segments using passive appliances (passive Alveolar Molding (pAM)). An advanced and

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * newborns/infants with non-syndromal (ns) unilateral cleft lip palate (UCLP) * signed informed consent by the parents or legal guardian Exclusion Criteria: * newborns/infants with syndromal (s) unilateral cleft lip palate (UCLP) * insufficient adherence and compliance by the parents or legal guardian * withdrawal of informed consent by the parents or legal guardian
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What it tests

  • passive Alveolar Molding
  • Nasoalveolar Molding
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Where

1 site
Department of Orthodontics and Orofacial Orthopedics, University Hospital of Erlangen-Nurnberg
Erlangen, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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