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Locomotor Recovery and Compensation Post-stroke (LRC)

RecruitingNAAges 18 Years - 85 YearsAllIndiana University
NCT05081713 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The proposed research will characterize of the time course of neurological and locomotor recovery as well as development of compensatory strategies throughout sub-acute and chronic phases post stroke. In addition, we will also investigate the extent to which measures of recovery and compensation are malleable and can be altered with specific interventions in both the early and late stages post-stroke. Delineation of the time course of development and magnitude of patterns of recovery and compensation should result in alternative predictive "rules' regarding how patients early post-stroke could recovery functional and neurological function.

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📋 Eligibility rules (as published)
Inclusion criteria: * individuals early post-stroke (\<15-30 days) * first ever stroke * unilateral hemiparesis * currently receiving inpatient rehabilitation * ability to follow 1-step commands * provision of informed consent * medical clearance from the rehabilitation physician to participate. \\ Exclusion criteria: * uncontrolled cardiovascular, metabolic or respiratory disease that limits exercise participation (e.g., congestive heart failure, resting blood pressure \> 200/110 mmHg, uncontrolled diabetes, end-stage renal disease) * absolute criteria for termination of exercise testing during initial and repeated ECG testing during graded exercise testing using ACSM guidelines . * other orthopedic or neurological disorder that limited walking prior to stroke
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What it tests

  • high-intensity training focused on stepping in variable contexts
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Where

1 site
Rehabilitation Hospital of Indiana
Indianapolis, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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