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Telephone-Based Support Programs for People With Epilepsy

RecruitingNAAges 18 Years - 99 YearsAllNYU Langone Health
NCT05082181 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a two-arm randomized controlled trial to compare telephone-based depression self-management (UPLIFT) to telephone-based support groups (BOOST). A sample of 120 English- and Spanish-speaking people with epilepsy (PWE) with elevated depressive symptoms will be enrolled. Both interventions are 8-week programs delivered in one-hour weekly sessions to groups of about 6 participants. Changes in depressive symptoms, quality of life and seizures will be assessed over 12 months. The trial will also examine mediators and moderators of treatment effects.

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📋 Eligibility rules (as published)
Inclusion Criteria: * adult (≥18 years of age); * diagnosed with epilepsy for at least one year; * fluent in English or Spanish; * elevated depressive symptoms (PHQ-9 score ≥10); * willing to participate in audiotaped group telephone sessions Exclusion Criteria: * severe depressive symptoms (PHQ-9 ≥20); * active suicidal ideation (PHQ-9 item #9 ≥1 or otherwise reported during screening); * active psychotic disorder (psychiatric diagnosis or antipsychotic medications in the EHR); * significant cognitive impairment (indicated in EHR or evident during screening)
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What it tests

  • UPLIFT (Using Practice and Learning to Increase Favorable Thoughts)
  • BOOST (Bringing Out Our Strength Together)
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Where

1 site
NYU Langone Health
New York, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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