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Study of Hospitalised Patients With Acute Respiratory Conditions

Recruitingn/aAges 18 Years - 90 YearsAllUniversity of Leicester
NCT05095090 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to learn about the short- and long-term outcomes of people admitted to hospital with an acute respiratory condition, including exacerbations of chronic lung disease, and to understand factors that may predict recovery, hospital readmission, length of hospital stay, and mortality. A group of people with chronic respiratory disease who are being followed in respiratory outpatient clinics and a healthy control group without lung disease will also take part. The main questions it aims to answer are: * Which clinical, physical, functional, and biological characteristics are associated with short-term outcomes after hospitalisation, including 30-day hospital readmission, length of hospital stay, and 30-day mortality? * Which characteristics are associated with longer-term recovery, future exacerbations, hospital readmissions, healthcare use, and mortal

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📋 Eligibility rules (as published)
Inclusion Criteria (Core study participants) 1. Hospital admission with an acute respiratory diagnosis, or currently under the care of hospital respiratory outpatient services for a chronic respiratory disease 2. Participant is willing \& able to give informed consent for participation in the study 3. Aged 18 years or above 4. Able (in the Investigators opinion) \& willing to comply with all study requirements Exclusion Criteria (Core study participants) 1. Unstable or life-threatening cardiac disease including myocardial infarction or unstable angina during current admission. 2. Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study. 3. Known pregnancy Inclusion Criteria (Healthy Controls) 1. Aged 18 years or above 2. No underlying respiratory disease as self-reported 3. Able (in the Investigators opinion) \& willing to comply with all study requirements Exclusion Criteria (Healthy Controls) 1. Hospitalised due to an acute respiratory illness in the last 6 weeks prior to consent 2. Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study. 3. Known pregnancy Additional inclusion and exclusion criteria for CHESTY sub-studies are detailed in the corresponding sub-study protocols.
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What it tests

  • Not listed
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Where

1 site
Glenfield Hospital
Leicester, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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