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Sentinel Lymph Node Biopsy for Cutaneous Squamous Cell Carcinoma of the Head and Neck

RecruitingNAAges 18 Years - anyAllIndiana University
NCT05108090 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to research if a type of biopsy known as sentinel lymph node biopsy (SLNB) can help in determining the rate of tumor deposits that are hard to detect and identify in node-negative cutaneous squamous cell carcinoma of the head or neck.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients ≥ 18 years old at the time of informed consent * Ability to provide written informed consent and HIPAA authorization * Primary or recurrent invasive cutaneous squamous cell carcinoma of the head or neck, clinically staged T2-T4 based on AJCC staging * Clinically and radiographically regional node-negative (no evidence of regional lymph node metastasis or distant metastasis) * Able to undergo general anesthesia for sentinel lymph node biopsy * Able to undergo CT scan with contrast or MRI with contrast * Undergo surgical resection (Moh's or micrographic resection or standard excision with sentinel lymph node biopsy) within 8 weeks of imaging Exclusion Criteria: * Clinical evidence of satellite lesions, in-transit, regional nodal or distant metastases * Known biopsy proven synchronous primary cutaneous squamous cell carcinoma * Pregnant patients * Patients unable to undergo general anesthesia * Patient unable to receive contrasted imaging studies * Patient unable to receive and/or allergic to 99m-Technetium sulfur colloid
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What it tests

  • sentinel lymph node biopsy (SLNB)
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Where

1 site
Indiana University Melvin & Bren Simon Cancer Center
Indianapolis, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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