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Redesigning the Surgical Pathway (PROMoTE)

RecruitingNAAges 60 Years - anyAllSunnybrook Health Sciences Centre
NCT05114876 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Cognitive complications, that is problems with thinking and memory, are incredibly common after surgery, occurring in 10-50% of all older surgical patients. These complications can take different forms, but one of the most common is postoperative delirium (POD), a short-term state of confusion. In addition to being stressful for patients and their families, POD is linked to longer hospital stays, increased costs, higher mortality rates and other problems after surgery. Despite this, POD is often not recognized by doctors and there are currently no effective medications to treat POD. However, simple strategies such as helping patients to sleep properly and remain hydrated, have been shown to help. This study is testing if a delirium-reduction program will reduce postoperative delirium (POD) in older surgical patients. The investigators will first test memory and thought processes before

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📋 Eligibility rules (as published)
Inclusion Criteria: * ≥ 60 years old * Undergoing major elective surgery (e.g., intra-abdominal, retroperitoneal, major orthopedic) with an expected postoperative stay of at least 1 night * Evidence of cognitive impairment on baseline screening tests (i.e. any score \< 90 on CBB or \>10 on S-OMCT) Exclusion Criteria: * Patients undergoing cardiac surgery * Patients undergoing intracranial neurosurgery * Patients with known substance use disorder (verbally declared by patients) * Unlikely to comply with study assessment (e.g., no fixed address, without access to internet/computer/phone).
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What it tests

  • Multicomponent delirium-risk prevention bundle
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Where

1 site
Sunnybrook Health Sciences Centre
Toronto, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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