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Pathogen-microbiome Interaction During Helicobacter Pylori Infection

Recruitingn/aAges 18 Years - anyAllUniversity Hospital Freiburg
NCT05121025 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Helicobacter pylori affects the gut microbiome in ways that are only partially understood. In which patients H. pylori causes severe disease and in whom it merely colonizes, possibly even with beneficial effects, is not understood. The investigators are pursuing the hypothesis that changes in the gut microbiome that can be easily measured in stool have such predictive value.

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📋 Eligibility rules (as published)
Inclusion Criteria: Patients: - * Male and female patients aged ≥ 18 years. * Specimens from patients undergoing tissue sampling, stool, and blood to rule out Helicobacter pylori infection * Written informed consent from patients. Volunteer subjects: - * Male and female (non-pregnant) volunteers between the ages of 18-65 years. * Written informed consent from volunteers. * No acute medical conditions * No regular medication use, and no antibiotic use in the last 4 weeks. Exclusion Criteria: Patients: - * Minor patients * Patients not capable of giving consent * Samples without sufficient residual material after standard diagnostic procedures * Samples from patients who have not given consent for testing Volunteer subjects: - * Subjects not capable of giving consent * Subjects with acute illnesses * Subjects older than 65 or younger than 18 years of age. * Pregnant women
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What it tests

  • Analysis of gut microbiome and immune signatures
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Where

1 site
Institute for Microbiology and Hygiene
Freiburg im Breisgau, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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