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Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk

RecruitingNAAges 14 Years - 20 YearsAllNorthwell Health
NCT05131035 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This 10 week intervention, Specific Cognitive Remediation with Surround (or SCORES), is designed to target processing speed, a cognitive domain related directly to social functioning, which in turn, represents a vulnerability factor for psychosis. This remotely-delivered intervention combining targeted cognitive training exercises and group support was developed to directly impact processing speed, and at the same time, boost motivation and engagement in adolescents at risk for schizophrenia and other psychotic disorders.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Meet Clinical High Risk (CHR) criteria on the Structured Interview for Psychosis Risk Syndromes, defined by the presence of at least one attenuated positive symptom at a moderate to severe level * A score representing 0.5 SD below the mean on Animal Naming, Trails A or BACS: Symbol Coding from the MATRICS Consensus Cognitive Battery (MCCB). Exclusion Criteria: * Any DSM 5 Schizophrenia-Spectrum diagnosis * Non-English speaking * Past or current history of a clinically significant central nervous system disorder (e.g., seizure disorder) * Estimated IQ\<70 * Significant head injury * Significant substance abuse * Significant visual or auditory impairment.
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What it tests

  • SCORES (Specific COgnitive Remediation with Support)
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Where

1 site
Northwell Health- The Zucker Hillside Hospital
Glen Oaks, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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