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Polysomnographic Titration of Non-invasive Ventilation in Motor Neurone Disease

RecruitingNAAges 18 Years - anyAllUniversity of Melbourne
NCT05136222 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

A two-arm, individual participant randomised controlled, assessor-blinded trial in 7 MND care centres across Australia will be undertaken.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age \>18 years * Clinical indication to commence long term NIV * Confirmed clinical diagnosis of underlying condition Exclusion Criteria: * Medically unstable * Hypoventilation attributable to medications with sedative/respiratory depressant side- effects * Use of NIV for more than 1 month in the previous 3 months * Inability to provide informed consent * Previous intolerance of NIV
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What it tests

  • Intervention polysomnography
  • Sham polysomnography
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Where

13 sites
Flinders Medical Centre
Adelaide, Australia
The Prince Charles Hospital
Brisbane, Australia
Motor Neurone Disease Australia
Canberra, Australia
Austin Health
Melbourne, Australia
Australian MND Registry
Melbourne, Australia
FightMND
Melbourne, Australia
Institute for Breathing and Sleep
Melbourne, Australia
Monash University
Melbourne, Australia

…and 5 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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