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Music Therapy for Patients With Alzheimer's Disease

RecruitingNAAges 18 Years - 89 YearsAllJohns Hopkins University
NCT05151562 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study is designed to assess the feasibility that individualized reminiscence-based virtual music therapy sessions can enhance autobiographical memory, mood, and cognition in patients with mild cognitive impairment (MCI) or mild dementia due to Alzheimer's Disease (AD). 60 patients with MCI or mild dementia due to AD will receive two 30 minutes reminiscence-targeted virtual music therapy interventions per week for 8 weeks (a total of 16 sessions). Participants' (or supported by the study partner) self-reported and measurable outcomes including cognitive, anxiety, quality of life, and autobiographical memory will be assessed before and after the 8-week course of treatment. Blood-oxygenation level-dependent (BOLD) in functional magnetic resonance imaging (fMRI) will also be also measured before and after the 8-week course of treatment.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18-89 * Mild Cognitive Impairment (MoCA score: 18-25) or Early AD (MoCA score: 17-24) Exclusion Criteria: * Head trauma, traumatic brain injury, or concussion with loss of consciousness for \>2 minutes * Claustrophobia incompatible with MRI scanning * Medical device incompatible with MRI scanning (e.g. cardiac pacemaker, implanted cardiac defibrillator, aneurysm brain clip, inner ear implant) * Prior history as a metal worker and/or certain metallic objects in the body * Exclusion Criteria will be carefully determined by the MRI screening form.
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What it tests

  • Virtual Music Therapy
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Where

1 site
Johns Hopkins School of Medicine
Baltimore, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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