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Transcutaneous Electrical Nerve Stimulation for Endometriosis-related Chronic Pain

RecruitingNAAges 18 Years - 100 YearsFemaleGöteborg University
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In plain words

What the trial is, and whether it could suit you

The study evaluates the effect of TENS (transcutaneous electrical nerve stimulation) as add-on treatment compared with conventional analgesic treatment in patients with endometriosis-related chronic pain. Patients with frequent pain and high pain intensity will be randomized to additional treatment with TENS or conventional treatment for 8 weeks to evaluate the acute effects of TENS treatment (n=40). Patients with endometriosis-related pain that is not frequent or without high pain intensity constitute an external control group. All patients in the study will receive TENS treatment for a total of 16 weeks, for evaluation of long-term effects of TENS treatment.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥18 years * Consents to participation in the study * Verified endometriosis (by laparoscopy or ultrasound). * Chronic endometriosis-related pain (\> 3 months), available for TENS treatment * Functioning, stable endometriosis-specific hormonal drug therapy. The endometriosis-specific drug therapy must be unchanged for the last 3 months and no gynecological surgical procedures for the treatment of endometriosis are planned during the next 7 months (during study participation). The endometriosis-specific drug therapy does not refer to analgesic therapy for symptom relief of endometriosis-related pain. Exclusion Criteria: * Patient with inability to understand and use written and spoken Swedish * Patient with pacemaker and/or ICD or other electronic implants * Patient with impaired sensation over the painful area * Malignant disease with an expected survival \<12 months * Alcohol or substance abuse * Serious untreated psychiatric illness and/or psychological condition that is the primary determinant of the patient's condition * Participating in another intervention study with possible impact on current study outcome measures * Patient who is using \>90 morphine equivalents/day * Patient who is electro-acupuncture * Pregnancy
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What it tests

  • Transcutaneous electrical nerve stimulation (TENS)
  • Conventional analgesic treatment
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Where

1 site
Pain Centre, Department of Anaesthesiology and Intensive Care Medicine Östra, Sahlgrenska University Hospital, Region Västra Götaland
Gothenburg, Sweden
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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