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Clinical Trial of Approaches to Prostate Cancer Surgery

RecruitingNAAges 40 Years - 80 YearsMaleWeill Medical College of Cornell University
NCT05155501 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a prospective, randomized controlled trial to compare cancer control and health-related quality of life following pelvic fascia-sparing radical prostatectomy versus standard radical prostatectomy. The investigators hypothesize that pelvic fascia-sparing radical prostatectomy will have similar cancer control (primary outcome) and sexual function outcomes; and significantly better urinary function, penile shortening/deformity and inguinal hernia risks as compared to radical prostatectomy.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Male sex * Age ≥40 years or ≤80 years * Scheduled for radical prostatectomy for clinically localized prostate cancer * Able to read and speak English or Spanish * Willingness to sign informed consent and adhere to the study protocol Exclusion Criteria: * Prior major pelvic surgery or radiotherapy * Suspicion of N1 disease (i.e., any lymph node greater than 1cm in maximal diameter)
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What it tests

  • Robot-assisted radical prostatectomy (RP)
  • Pelvic fascia-sparing robot-assisted radical prostatectomy (PFS-RP)
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Where

9 sites
Beckman Research Institute of City of Hope
Duarte, United States
Georgetown University
Washington D.C., United States
Northwestern University
Chicago, United States
Johns Hopkins University
Baltimore, United States
Beth Israel Deaconess Medical Center (BIDMC)
Boston, United States
Hackensack Meridian Health
Hackensack, United States
NewYork-Presbyterian Queens
Flushing, United States
Memorial Sloan Kettering Cancer Center
New York, United States

…and 1 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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