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Blood Warming in Preterm Infants to Decrease Hypothermia

RecruitingNAAges 24 Weeks - 32 WeeksAllUniversity of South Carolina
NCT05170633 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Background/significance: Over 100,000 early preterm infants are born annually in the United States and suffer morbidity and mortality during hospitalization in a neonatal intensive care unit. One such condition is hypothermia. Hypothermia has been defined as a contributor of neonatal morbidity by The World Health Organization. Another acute morbidity is anemia in preterm infants due to the prematurity and frequent laboratory testing. Anemia requires correction with a packed red blood cells (PRBC) transfusion. Researchers have previous noted hypothermia during PRBC transfusions in preterm infants. Objective: To use a commercial blood warmer in the neonatal intensive care setting to prevent hypothermic body temperatures (\<36.5°C) in very preterm infants during PRBC transfusions. Process: Based on a completed national survey of neonatal intensive care nurses and PRBC transfusion practice

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📋 Eligibility rules (as published)
Inclusion Criteria: * Any infant born at PRISMA Health Richland hospital * less than 32 weeks gestational age by obstetrical dating as indicated in the electronic medical chart * admitted to the neonatal intensive care unit receiving one PRBC transfusion within the first month of life. Exclusion Criteria: * Infants having neurological anatomical abnormalities or major brain hemorrhage (Grade III or IV), because neurological damage can interfere with thermal control.
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What it tests

  • Ranger blood warmer (3M Healthcare, Oakdale, Minnesota)
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Where

1 site
Kayla Everhart
Columbia, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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