🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Imaging the Interplay Between Axonal Damage and Repair in Multiple Sclerosis

Recruitingn/aAges 18 Years - 80 YearsAllUniversity Hospital, Basel, Switzerland
NCT05177523 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

This project is to: 1. Quantify differences in axonal integrity and organization in aMS versus naPMS patients. 2. Quantify changes in axonal integrity and organization in aMS versus naPMS patients over a two-year period. 3. Validate the combination of imaging parameters that best differentiate aMS versus naPMS patients using histopathology.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria for patients: * Patients may be diagnosed with: 1. active RRMS (n=100): Relapsing-remitting course and \> 1 clinical relapse and/or signs of MRI activity (\> 1 Gd enhancing lesion) during the last year before study enrollment. 2. non-active PMS (n=100): Progressive course (PPMS or SPMS) and no clinical relapses and/or signs of MRI activity during the last year before study enrollment. * Age 18-80 years old * No other neurological or psychiatric disorder Inclusion criteria for healthy controls: * Age 18-80 years old * No other neurological or psychiatric disorder Exclusion Criteria for patients and healthy controls: * Pregnancy * Contraindication to MRI (eg, claustrophobia, metallic implants, pacemaker etc). * Inability to give consent
💊

What it tests

  • MRI
  • Neurocognitive examination for healthy subjects
  • blood sampling
📍

Where

1 site
University Hospital Basel, Department of Neurology
Basel, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy