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Autologous Platelet Rich Plasma Intraovarian Infusion for Poor Responders

RecruitingPhase 2, Phase 3Ages 35 Years - 47 YearsFemaleGenesis Athens Clinic
NCT05181748 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Autologous platelet rich plasma (PRP) intraovarian infusion may improve ovarian response to controlled ovarian stimulation as well as the hormonal profile of poor ovarian response infertile women subjected to intracytoplasmic sperm injection (ICSI) treatment.

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📋 Eligibility rules (as published)
Inclusion Criteria: Poor Ovarian Response according to Bologna Criteria (fulfilling 2 out of 3 of the following): 1. Age ≥ 40 years 2. AMH \< 1.1 ng/ml OR AFC \< 7 3. ≤ 3 oocytes with a conventional stimulation protocol * Discontinuation of any complementary/adjuvant treatment including hormone replacement and acupuncture, for at least three months prior to recruitment. * Willing to comply with study requirements Exclusion Criteria: * Any pathological disorder related to reproductive system anatomy * Cycle irregularities * Amenorrhea * Endometriosis * Adenomyosis * Fibroids and adhesions * Infections in reproductive system * Current or previous diagnosis of cancer in reproductive system * History of familiar cancer in reproductive system * Severe male factor infertility * Prior referral for Preimplantation Genetic Testing (PGT) -Ovarian inaccessibility -Endocrinological disorders (Hypothalamus- * Pituitary disorders, thyroid dysfunction, diabetes mellitus, metabolic syndrome) * BMI\>30 kg/m2 or BMI\<18.5 kg/m2 * Systematic autoimmune disorders
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What it tests

  • Autologous platelet rich plasma
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Where

1 site
Genesis Athens Clinic
Athens, Greece
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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