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โ† Trials
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Neurostimulation for the Treatment of Post-Stroke Aphasia

RecruitingNAAges 18 Years - 80 YearsAllQVITI S.A.
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In plain words

What the trial is, and whether it could suit you

The aim of the trial is to determine whether 75Hz transcranial alternating current stimulation (tACS) synchronized with therapeutic linguistic tasks is an effective form of therapy for post-stroke aphasia.

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๐Ÿ“‹ Eligibility rules (as published)
Individuals with aphasia (assessed using the Boston Diagnostic Aphasia Examination) who perform the Naming Task in the range of 10%-60% accuracy will be included in the study. The overall baseline score in the Naming Task will be estimated from the two baseline measurements. Inclusion Criteria: * diagnosis of aphasia: Broca's or mixed (based on the assessment of a Speech Language Pathologist). * presence of a focus of injury in the left hemisphere (within one hemisphere only) as a result of the first ischemic or hemorrhagic stroke (based on CT/MRI examination); * chronic stage of the disease - time since the stroke occurred over 6 months. * ability to achieve an accuracy in the Naming Task of 10-60%. * 18-80 years * right-handedness before the stroke. * ability to give informed written consent. * fluency in English. Exclusion Criteria: * severe cognitive, auditory or visual impairment that would preclude cognitive and language testing - inability to follow a two-step command. * presence of metal implants in the skull. * presence of major untreated or unstable psychiatric disease. * history of epilepsy or seizures. * ongoing medication that increases the risk of epileptic seizures. * presence in the body of cardiac stimulator, pacemaker or vagus nerve stimulator (implanted). * history of speech, language, hearing, or intellectual disability during childhood. * pregnancy (based on declarations) Exclusion criteria during the trial: * high intolerance to stimulation. * occurrence of an epileptic seizure. * other previously absent neurological or mental symptoms Withdrawal criteria: * high intolerance to stimulation (participants experience severe discomfort during stimulation); * occurrence of an epileptic seizure; * other previously absent neurological, physical or mental symptoms.
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What it tests

  • tACS
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Where

2 sites
Think & Speak Lab at Shirley Ryan AbilityLab
Chicago, United States
Abilities Research Center at Mount Sinai
New York, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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