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Association of Intrahepatic Cholestasis of Pregnancy and Chronic Placental Inflammation

Recruitingn/aAges 18 Years - 60 YearsFemaleUniversity Hospital, Brest
NCT05197387 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This observational prospective study will help to determine if an immune process similar to allograft rejection is responsible for the occurrence of an intrahepatic cholestasis of pregnancy (ICP). If so, it would suggest the potential benefit of immunomodulatory therapeutics.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult pregnant woman with singleton For cases: diagnosis of intrahepatic cholestasis of pregnancy For controls: no diagnosis of ICP Exclusion Criteria: * Women under 18 years old * Women under legal protection * Gemellar pregnancies * Delivery before 22 Weeks of gestation * Medical termination of pregnancy * Acute chorioamniotitis, in particular those due to the following pathogens: toxoplasmosis, rubella, CMV, herpes virus * Premature rupture of membranes \<37SA * Women infected by covid-19 in the month before delivery
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What it tests

  • Not listed
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Where

11 sites
CHU Angers
Angers, France
Polyclinique KERAUDREN
Brest, France
CHU de Brest
Brest, France
CHU de Caen
Caen, France
CH de Chambery
Chambéry, France
CH Bretagne Sud
Lorient, France
CHU Nantes
Nantes, France
CH de Quimper
Quimper, France

…and 3 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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