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โ† Trials
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Sutures Versus Polyglactin Mesh in Hiatal Hernia Repair

RecruitingNAAges 18 Years - anyAllOulu University Hospital
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In plain words

What the trial is, and whether it could suit you

Paraesophageal hernia causes pain, heartburn, regurgitation, anemia and in extreme, life-threatening strangulation. For symptomatic patients, laparoscopic surgery is offered which includes hiatal defect closure and antireflux surgery. However, recurrence rates are high between 12 and 42%. In order to reduce recurrences, mesh has been used with various materials and techniques with conflicting results. Non-absorbable mesh has been linked with adverse events including erosion of esophageal wall. Traditionally used biological mesh materials are expensive and therefore problematic in routine use. Use of polyglactin (Vicrylยฎ) mesh, which degrades in 6-8 week, has been reported in paraesophageal hernia surgery. Previously, no randomized controlled trial comparing sutures only and polyglactin mesh has been performed. In this trial, the aim was to randomize total of 110 patients to receive sutur

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Over 18 years old * Type III-IV PEH with either radiologic or endoscopic confirmation * Scheduled for laparoscopic PEH repair * The informed consent is acquired Exclusion Criteria: * Need for esophagus lengthening procedure (Collis gastroplasty) * Recurrent PEH * Emergency surgery * No written consent
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What it tests

  • Polyglactin mesh
  • Sutures only
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Where

1 site
Oulu University Hospital
Oulu, Finland
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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