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Heparinization vs Salinization of the Peripheral Venous Catheter

RecruitingNAAges 18 Years - 100 YearsAllConsorci Sanitari de l'Alt Penedès i Garraf
NCT05209841 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Randomized, double-blind clinical trial to compare the efficacy of catheter sealing with saline, compared to low-dose heparin. 3,450 patients hospitalized at the Hospital Residencia Sant Camil, in Catalonia (Spain), will be randomized to each branch of study. The primary outcome will be the percentage of catheters removed due to obstruction in each branch of study. As secondary outcomes, the number of catheter-associated phlebitis, catheter-associated bacetrihemia, extravasation, and catheter loss will be measured. For the primary outcome, a superiority analysis will be carried out in terms of the percentage of obstructed catheters in each branch of the study.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients older than 18 yo, admitted to the Hospital Residencia Sant Camil * Patients with at least one peripheral venous line for discontinuous treatment, which has not been channeled in a medical emergency situation. * Written informed consent Exclusion Criteria: * Allergy to heparin * Patients treated with unfractionated sodium heparin. * Patients in dialysis * Patients with a venous catheter indicated for diagnosis tests. * Patients with a venous catheter indicated for blood transfusion * Severe heparin-induced thrombocytopenia in recent months * Active uncontrollable bleeding during admission * Brain aneurysm or dissecting aorta, except in association with corrective surgery. * Confirmed / suspected cerebrovascular hemorrhage * Severe uncontrolled hypertension * Severe alterations in platelet coagulation \<30,000, TP\> 1.7 APTT ratio\> 1.7 ratio. * Patient included in another clinical trial with drugs or procedures that may affect the patency of venous catheters.
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What it tests

  • Low dose heparin
  • Normal saline
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Where

1 site
Hospital Residència Sant Camil
Sant Pere de Ribes, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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