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General Anesthetics-related Changes in Prefrontal EEG During Pediatric Surgical Anesthesia

Recruitingn/aAges 1 Minute - 18 YearsAllPeking University First Hospital
NCT05210764 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The change profiles of indices derived from pEEG such as phase-amplitude coupling and bicoherence based on individual general anesthetics in children have not been examined in previous literature. Whether those indices have the abilities to predict individual drug-related anesthesia depth in children need to be explored.

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📋 Eligibility rules (as published)
Inclusion Criteria: * patients aged 0-18 years, American Society of Anesthesiologists Physical Status I-II, scheduled for elective surgery in Peking University First Hospital. Exclusion Criteria: * Preterm patients; * Height and weight not within the standard ranges for respective ages; * Surgery for head or heart; * Patients with muscular, neurologic or psychiatric diseases; * Patients with Congenital anomaly or hereditary diseases; * Patients with medication abuse; * Allergy to medication including propofol, sevoflurane, and ketamine; * Allergy to beans; * Refusal to participate the study by guardians.
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What it tests

  • propofol
  • sevoflurane
  • S-ketamine
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Where

1 site
Peking University First Hospital
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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