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Modeling of Intracerebral Vascularization After Extracorporeal Membrane Oxygenation in Children

Recruitingn/aAges any - 17 YearsAllAssistance Publique - Hôpitaux de Paris
NCT05237232 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Extra corporeal membrane oxygenation (ECMO) is a transient supplementation technique that alleviates hemodynamic and ventilatory failure. Its implementation requires carotid arterial and jugular venous cannulation in newborns or children weighing less than 20 kg. The impact of ECMO on arterial circulation was studied by Doppler ultrasound and shows a redistribution of flows within the circle of Willis. This study aims to model cerebral flow in children who have been cared from jugulocarotid ECMO and compare cerebral hemodynamics according to the technique of reconstruction of the common carotid artery after decanulation (reconstruction or ligation).

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📋 Eligibility rules (as published)
Inclusion Criteria: For everyone : 1. Information and non-opposition of holders of parental authority 2. Newborn, infant and child \<20kg 3. Hospitalization in pediatric and neonatal intensive care unit (PICU) of Trousseau Hospital 4. Performing a Magnetic Resonance Angiography (MRA) as part of the treatment For patients treated with ECMO: study population 5. Hemodynamic or respiratory failure 6. Requiring the use of extracorporeal circulation with jugulo-carotid cannulation 7. Weaned alive off Extra corporeal membrane oxygenation (ECMO) For patients with hypoxic-ischemic encephalopathy: control population 8. hypoxic-ischemic encephalopathy diagnosed at birth Exclusion Criteria: 1. Contraindication to MRA 2. Opposition of holders of parental authority
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What it tests

  • Magnetic Resonance Angiography (MRA) additional acquisition time
  • Modeling cerebral vascularization
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Where

1 site
Hôpital Trousseau
Paris, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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