🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Family Involvement in Treatment for PTSD (FIT-PTSD): A Brief, Feasible Method for Enhancing Outcomes, Retention, and Engagement

RecruitingNAAges 18 Years - anyAllVA Office of Research and Development
NCT05267665 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Although effective treatments for PTSD exist, high rates of treatment dropout and sub-optimal response rates remain common. Incorporating family members in treatment represents one avenue for improving outcomes and providing Veteran-centered care, and surveys of Veterans in outpatient VA PTSD care indicate that 80% desire family involvement. The VA has invested many years and millions of dollars on the dissemination of Cognitive Processing Therapy (CPT) and Prolonged Exposure (PE) for PTSD. A family-based intervention that complements these two first-line treatments would capitalize on existing treatment infrastructure while also potentially boosting outcomes and retention. Preliminary testing of the proposed Brief Family Intervention (BFI) resulted in 50% less dropout from CPT/PE among Veterans whose family members received the BFI. There was also a large impact on PTSD symptoms at 16

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: Inclusion criteria for Veterans will include: * a current DSM-5 diagnosis of PTSD * Veteran status * willing to have a family member involved in the study * has recently begun or is currently initiating individual CPT or PE (completed no more than 3 sessions of the protocol at the time of the baseline assessment) * If taking psychotropic medication, the Veteran must be on a stable dose for at least 30 days. Inclusion criteria for family members will include: * age 18 or older, family member of the Veteran (significant other, parent, adult child, sibling, etc.) * currently having frequent contact with the Veteran (three or more times per week) Exclusion Criteria: Exclusion criteria for Veterans will include: * current engagement in couple/family treatment with the identified family member participant * current severe substance use disorder (mild/moderate use disorders will not be excluded; any level of nicotine or caffeine use disorder accepted) * current psychosis or unstable bipolar disorder diagnosis * high suicidal risk * significant cognitive impairment Exclusion criteria for family members will include: * same as listed for Veterans. Additionally * family members will NOT be permitted to participate if they meet criteria for current PTSD
💊

What it tests

  • Brief Family Intervention (BFI)
📍

Where

3 sites
VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA
Boston, United States
Durham VA Medical Center, Durham, NC
Durham, United States
Cincinnati VA Medical Center, Cincinnati, OH
Cincinnati, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy