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โ† Trials
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Home-based Heat Therapy for Type 2 Diabetes

RecruitingNAAges 45 Years - 75 YearsAllMontreal Heart Institute
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In plain words

What the trial is, and whether it could suit you

Insulin resistance and hyperglycemia predispose individuals with type 2 diabetes mellitus (T2DM) to endothelial dysfunction and a greater risk of cardiovascular diseases (CVD). Increased CVD risk in individuals with T2DM persists despite optimal pharmacological therapy, highlighting the need to identify complementary lifestyle interventions that improve cardiometabolic functions in this population. Evidence from animal models suggests that heat exposure improves metabolic functions. Notably, weekly heat exposure for 16 weeks blunts hyperinsulinemia and hyperglycemia induced by a high fat diet in mice. In parallel, studies in humans have shown that heat exposure improves vascular endothelial function. Based on such findings, it has been suggested that heat therapy may represent an effective lifestyle intervention to improve cardiometabolic functions. However, only 1 study has examined the

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age 45-75 years * Diagnosis of type 2 diabetes mellitus โ‰ฅ1 year * Stable medication โ‰ฅ12 weeks Exclusion Criteria: * Class 3 obesity * Hypertension not controled by medication * Diagnosis of cardiac, renal and/or pulmonary disease * Diagnosis of severe neuropathy and/or retinopathy * Insulin therapy * Fasting plasma triglycerides \>5.0 mmol/L * Fasting total cholesterol \>7 mmol/l
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What it tests

  • Thermoneutral water
  • Hot water
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Where

1 site
Centre ร‰PIC, Montreal Heart Institute
Montreal, Canada
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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