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Coronary Microvascular Dysfunction Assessments in Myocardial Infarction With Non-Obstructive Coronary Arteries

Recruitingn/aAges 19 Years - anyAllChonnam National University Hospital
NCT05272618 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

To compare clinical outcomes of myocardial infarction with non-obstructive coronary arteries (MINOCA) according to the coronary microvascular dysfunction (CMD), evaluated by optical coherence tomography (OCT), invasive and non-invasive coronary physiologic assessment.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Subject with age ≥19 years and acute myocardial infarction * Rise and/or fall of cardiac troponin with one level \>99 percentile plus ischemic signs/symptoms * Subject with non-obstructive coronary arteries * \<50% diameter stenosis or * fractional flow reserve (FFR) \>0.80 ③ Subject without previous history of coronary artery disease * Subject who performed invasive coronary angiography within 24 hours after presentation ⑤ Subject who eligible for invasive and non-invasive coronary physiologic assessment Exclusion Criteria: * Subject with obstructive coronary arteries * Subject with alternate diagnosis including sepsis, pulmonary embolism, myocarditis, Takotsubo syndrome, spontaneous coronary dissection, and other cardiomyopathies. * Subject with cardiogenic shock or cardiac arrest ④ Subject who has non-cardiac co-morbid conditions with life expectancy \<1 year ⑤ Subject or lactating women ⑥ Subject unable to provide consent
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What it tests

  • Intravascular imaging (OCT), Invasive physiologic assessment (FFR, CFR, IMR), or Non-invasive physiologic assessment (N-13 ammonia PET)
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Where

1 site
Chonnam National University Hospital
Gwangju, South Korea
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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