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The Association Between Non-vitamin K Antagonist Oral Anticoagulant Therapy and Acute Stroke Severity and Post Stroke Short-term and Long-term Outcomes.

Recruitingn/aAges 20 Years - anyAllNational Taiwan University Hospital
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In plain words

What the trial is, and whether it could suit you

Non-vitamin K antagonist oral anticoagulant (NOAC) is the first line therapy to prevent thromboembolism in atrial fibrillation (AF) patients. Previous investigation showed that preceding NOAC therapy was associated with lower severity of ischemic stroke, but with higher in-hospital mortality in intracerebral hemorrhage (ICH), as compared with antithrombotic agent non-users. Measurement of NOAC level upon acute stroke aids the critical decision of acute management. Real-world data regarding the relationship between the NOAC adherence, the appropriateness of NOAC regimen, or NOAC level in acute stroke and the stroke severity or short-term outcome is lacking. Further, optimal selection for long-term stroke prevention among patients with acute stroke during NOAC therapy remains unclear. Specific purpose: To analyze the association between NOAC adherence or NOAC level upon acute stroke and s

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Atrial fibrillation * Under dabigatran, rivaroxaban, apixaban or edoxaban therapy. * Developing ischemic stroke, transient ischemic attack or intracranial hemorrhage during NOAC therapy. Exclusion Criteria: * Refuse to provide blood sample for non-vitamin K antagonist oral anticoagulant (NOAC) concentration measurement. * Refuse to provide informed consent.
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What it tests

  • Blood sampling to test drug level
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Where

1 site
National Taiwan University Hospital
Taipei, Taiwan
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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