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Ketorolac in Upper Extremity Tendinopathy and Arthropathy

RecruitingPhase 4Ages 18 Years - anyAllEmory University
NCT05292339 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Osteoarthritis (OA) and inflammatory conditions of the tendons and joints of the shoulder, elbow, hand, and wrist are common yet disabling diseases. Standard management utilizes conservative measures to minimize pain and improve function. Conservative pharmacological management commonly includes corticosteroid and ketorolac injections which have been well investigated as a modality of pain control and improved function in large joint OA. However, fewer studies yielding mixed results on the duration of symptomatic relief exist for arthropathy and tendinopathy of these joints. The goal of this study is to evaluate the efficacy of ketorolac and triamcinolone injections for common shoulder, elbow, wrist, and hand tendinopathy or arthropathy. Participants will be blinded to the treatment received. The duration of an individual participant's participation in this study is 24 weeks. During th

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18 or older, * symptomatic tendinopathy or arthropathy of the shoulder, elbow, hand, or wrist who have not undergone prior surgical treatment for their condition. * Diagnoses may include trigger finger, De Quervain's tenosynovitis, radiocarpal osteoarthritis, first carpometacarpal (CMC) joint osteoarthritis, metacarpophalangeal joint osteoarthritis, or proximal interphalangeal joint osteoarthritis. Exclusion Criteria: * Patients under the age of 18, * Patients who have undergone prior triamcinolone or ketorolac injections within the past 6 months, * Patients who have undergone prior surgical treatment for their hand condition, * Patients with allergy or contraindication to triamcinolone or ketorolac injection, * Patients with an active infection at the treatment site \[active infection defined as cellulitis, purulence, fever, chills, or presence of elevated inflammatory markers, ie. white blood cells (WBC), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP)\].
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What it tests

  • Triamcinolone injection to the shoulder, elbow, wrist, or hand
  • Ketorolac injection to the shoulder, elbow, wrist, or hand
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Where

4 sites
Emory Saint Joseph's Hospital
Atlanta, United States
Emory University Orthopaedic and Spine Center
Atlanta, United States
12 Executive Park Drive
Atlanta, United States
Emory University Orthopaedic and Spine Hospital
Atlanta, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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