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Labetalol or Nifedipine for Control of Postpartum Hypertension: A Randomized Controlled Trial

RecruitingPhase 4Ages 19 Years - anyFemaleNebraska Methodist Health System
NCT05309460 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Randomized trial comparing risk of hospital readmission and hypertensive complications between patients managed on Labetalol compared to Nifedipine.

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📋 Eligibility rules (as published)
Inclusion Criteria: Any patient admitted for delivery by cesarean or vaginal delivery at 24 weeks gestation or greater with hypertension(HTN). Hypertension will be defined during the study as either a systolic blood pressure ≥140mmHg or diastolic blood pressure ≥90mmHg on two occasions at least 4 hours apart. This definition is consistent with the ACOG definition for pregnancy related HTN. Following enrollment, treatment will be escalated at discretion of primary provider with the goal of normotension. Exclusion Criteria: History of moderate persistent asthma, coronary artery disease, heart failure, AV heart block, pulmonary edema * Contraindication to either Nifedipine or Labetalol * HR \<60 or \>110 * Native language other than English or Spanish
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What it tests

  • Labetalol Oral Tablet
  • NIFEdipine ER
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Where

1 site
Nebraska Methodist Women's Hospital
Omaha, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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