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Prospective Evaluation of Pencil Beam Scanning Proton Therapy for Previously Irradiated Tumors

RecruitingNAAges 18 Years - anyAllThe New York Proton Center
NCT05313191 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical research trial is to study the use of differing investigational doses and scheduling for Proton Therapy for tumors previously treated with radiation therapy. Generally, when patients are first treated for cancer with radiation therapy, they are treated with traditional photon (or x-ray) radiation therapy, which uses high-energy waves to kill tumor cells. In some cases, the cancer either returns or a new tumor can present in a different part of the body. With the usual radiation treatment, the photon beams travel all the way through the body. As a result, healthy tissues in front of and behind the tumor are exposed to radiation. Physicians who treat these cases where the tumor has returned often use a much lower dose of radiation to prevent patients from experiencing serious and long-term side-effects. This dose is often not strong enough to destroy the cancerous

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18 years * Patient provides study specific informed consent prior to study entry. * Documented history and physical exam within 90 days prior to registration. * ECOG PS 0, 1, or 2 within 90 days prior to registration Exclusion Criteria: * Non malignant systemic disease that would preclude the patient from receiving study treatment or would prevent required follow up. * Prior invasive non study malignancy unless disease free for ≥ 3 years * Non melanoma skin cancer, low risk prostate cancer, well differentiated thyroid cancers, in situ carcinomas of the oral cavity, cervix, and other organs, and tumors that are not thought to impact the life expectancy of the patient are permissible. * History of active connective tissue disorder (i.e., systemic lupus erythematosus, scleroderma), dermatomyositis, xeroderma pigmentosum
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What it tests

  • Pencil Beam Scanning Proton Therapy
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Where

1 site
The New York Proton Center
New York, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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